A flavonoid; inhibits the production of DPPH radicals by 17.2% and the formation of superoxide radicals by 48.3% in cell-free assays; decreases the rate of LDL oxidation ex vivo in isolated hamster plasma; increases proliferation of MC3T3-E1 cells and reverses the antiproliferative effect of PD 98059; increases the expression of the osteogenic differentiation markers Runx2

Neoeriocitrin – 5 mg

Brand:
Cayman
CAS:
13241-32-2
Storage:
-20
UN-No:
Non-Hazardous - /

Neoeriocitrin is a flavonoid that has been found in C. paradisi and has antioxidative and osteogenic activities.{48344,48345} It inhibits the production of 2,2-diphenyl-1-picrylhydrazyl (DPPH; Item No. 14805) radicals by 17.2% and the formation of superoxide radicals by 48.3% in cell-free assays, as well as decreases the rate of LDL oxidation ex vivo in isolated hamster plasma. Neoeriocitrin (2 µg/ml) increases proliferation of MC3T3-E1 osteoblast percursor cells and reverses the antiproliferative effect of the MEK1 inhibitor PD 98059 (Item No. 10006726).{48345} It also increases the expression of the osteogenic differentiation markers Runx2, Type 1 collagen, and osteocalcin.  

 

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SKU: 25839 - 5 mg Category:

Description

A flavonoid; inhibits the production of DPPH radicals by 17.2% and the formation of superoxide radicals by 48.3% in cell-free assays; decreases the rate of LDL oxidation ex vivo in isolated hamster plasma; increases proliferation of MC3T3-E1 cells and reverses the antiproliferative effect of PD 98059; increases the expression of the osteogenic differentiation markers Runx2, Type 1 collagen, and osteocalcin

Formal name: (2S)-7-[[2-O-(6-deoxy-α-L-mannopyranosyl)-β-D-glucopyranosyl]oxy]-2-(3,4-dihydroxyphenyl)-2,3-dihydro-5-hydroxy-4H-1-benzopyran-4-one

Synonyms:  Eriodictyol 7-O-neohesperidoside

Molecular weight: 596.5

CAS: 13241-32-2

Purity: ≥98%

Formulation: A crystalline solid

Product Type|Biochemicals|Natural Products|Flavonoids||Product Type|Biochemicals|Ox Stress Reagents|Antioxidants||Research Area|Endocrinology & Metabolism|Bone Growth & Remodeling||Research Area|Oxidative Stress & Reactive Species|Antioxidant Activity||Research Area|Oxidative Stress & Reactive Species|Lipid Peroxidation||Research Area|Oxidative Stress & Reactive Species|Reactive Oxygen|Non-enzymatic

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