An antagonist of monoamine transporters and receptors in the CNS (Kds = 26

Nefazodone (hydrochloride) – 1 g

Brand:
Cayman
CAS:
82752-99-6
Storage:
22
UN-No:
Non-Hazardous - /

Nefazodone is an antagonist of monoamine transporters and receptors in the CNS (Kds = 26, 48, and 80 nM for 5-HT2A, α2-adrenergic, and D2 receptors, respectively).{22877,25803,32156} It has shown efficacy as an antidepressant, reducing anxiety and agitation symptoms, in clinical trials.{31639,32156}  

 

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SKU: 10012642 - 1 g Category:

Description

An antagonist of monoamine transporters and receptors in the CNS (Kds = 26, 48, and 80 nM for 5-HT2A, α2-adrenergic receptor, and D2 receptors, respectively)

Formal name: 2-[3-[4-(3-chlorophenyl)-1-piperazinyl]propyl]-5-ethyl-2,4-dihydro-4-(2-phenoxyethyl)-3H-1,2,4-triazol-3-one, monohydrochloride

Synonyms:  BMY 13754|MJ13754-1

Molecular weight: 506.5

CAS: 82752-99-6

Purity: ≥98%

Formulation: A crystalline solid

Product Type|Biochemicals|Receptor Pharmacology|Antagonists||Product Type|Biochemicals|Transporter & Exchanger Modulators||Research Area|Neuroscience|Behavioral Neuroscience|Anxiety||Research Area|Neuroscience|Behavioral Neuroscience|Depression

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