A selective inhibitor of the gelatinases MMP-2 and MMP-9

ND-336 – 500 µg

Brand:
Cayman
CAS:
1807453-83-3
Storage:
-20
UN-No:
Non-Hazardous - /

ND-336 is a selective inhibitor of the gelatinases matrix metalloproteinase-2 (MMP-2) and MMP-9, as well as MMP-14 (Kis = 85, 150, and 120 nM, respectively).{32106} It has minimal effect on other MMPs. ND-336 accelerates diabetic wound healing in mice by lowering inflammation and by enhancing angiogenesis and re-epithelialization of the wound.{32106}  

 

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Description

A selective inhibitor of the gelatinases MMP-2 and MMP-9, as well as MMP-14 (Kis = 85, 150, and 120 nM, respectively); accelerates diabetic wound healing in mice

Formal name: 4-[4-[(2-thiiranylmethyl)sulfonyl]phenoxy]-benzenemethanamine, monohydrochloride

Synonyms: 

Molecular weight: 371.9

CAS: 1807453-83-3

Purity: ≥95%

Formulation: A crystalline solid

Product Type|Biochemicals|Small Molecule Inhibitors|MMPs||Research Area|Endocrinology & Metabolism|Metabolic Diseases|Diabetes||Research Area|Immunology & Inflammation

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