A naturally occurring macrolide polyene used to treat fungal infections

Natamycin – 100 mg

Brand:
Cayman
CAS:
7681-93-8
Storage:
-20
UN-No:
Non-Hazardous - /

Natamycin is a naturally-occurring macrolide polyene antifungal agent produced during fermentation by the bacterium S. natalensis, commonly found in soil. With minimal inhibitory concentrations ranging from 4-64 μM, natamycin is used to treat fungal infections, including Candida, Aspergillus, Cephalosporium, Fusarium, and Penicillium.{21495,21492,21494} Natamycin blocks fungal growth by binding specifically to ergosterol with an apparent affinity of ~100 μM, but it does not permeabilize cell membranes as other polyene antibiotics are known to do.{21492} Natamycin is also used in the food industry as a preservative.{21493}  

 

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SKU: 11634 - 100 mg Category:

Description

A naturally occurring macrolide polyene used to treat fungal infections, including Candida, Aspergillus, Cephalosporium, Fusarium and Penicillium (minimal inhibitory concentrations ~ 4-64 μM); also used in the food industry as a preservative

Formal name: (5R,7R,24S)-22R-[(3S-amino-3,6-dideoxy-β-D-mannopyranosyl)oxy]-1R,3S,26S-trihydroxy-12R-methyl-10-oxo-6,11,28-trioxatricyclo[22.3.1.05,7]octacosa-8E,14E,16E,18E,20E-pentaene-25R-carboxylic acid

Synonyms:  Antibiotic A 5283|CL 12,625|Delvocid|E 235|Mycophyt|Myprozine|Pimaricin|Synogil|Tennecetin

Molecular weight: 665.7

CAS: 7681-93-8

Purity: ≥95%

Formulation: A crystalline solid

Product Type|Biochemicals|Antifungals|Polyenes||Product Type|Biochemicals|Natural Products|Microbial Metabolites||Research Area|Immunology & Inflammation||Research Area|Infectious Disease|Fungal Diseases|Aspergillosis||Research Area|Infectious Disease|Fungal Diseases|Candidiasis

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