A flavanone; reduces airway sensitivity

Narirutin – 10 mg

Brand:
Cayman
CAS:
14259-46-2
Storage:
-20
UN-No:
Non-Hazardous - /

Narirutin is a flavanone originally isolated from C. paradisi that has anti-inflammatory and antidepressant-like activities.{37744} It reduces airway sensitivity, eosinophil counts and IL-4 levels in bronchoalveolar lavage fluid (BALF), and serum IgE levels in an ovalbumin mouse model of allergic eosinophilic airway inflammation when administered at a dose of 10 mg/kg.{37745} Narirutin decreases immobility in the forced swim test and latency to feeding in the novelty-suppressed feeding test, indicating antidepressant-like activity in a mouse model of chronic mild stress-induced depression.{37746}  

 

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SKU: 25124 - 10 mg Category:

Description

A flavanone; reduces airway sensitivity, eosinophil counts and IL-4 levels in BALF, and serum IgE levels in a mouse model of ovalbumin-induced airway inflammation at 10 mg/kg; decreases immobility in the forced swim test and latency to feeding in the novelty-suppressed feeding test, indicating antidepressant-like activity in mice

Formal name: (2S)-7-[[6-O-(6-deoxy-α-L-mannopyranosyl)-β-D-glucopyranosyl]oxy]-2,3-dihydro-5-hydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one

Synonyms:  (2S)-Narirutin|Naringenin-7-O-Rutinoside

Molecular weight: 580.5

CAS: 14259-46-2

Purity: ≥98%

Formulation: A crystalline solid

Product Type|Biochemicals|Natural Products|Flavonoids||Research Area|Immunology & Inflammation|Allergy||Research Area|Immunology & Inflammation|Innate Immunity||Research Area|Neuroscience|Behavioral Neuroscience|Depression

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