Description
An ionophore antibiotic used in veterinary practice as a coccidiostat for gastrointestinal parasites; inhibits NF-κB signaling via inhibition of IκBα phosphorylation (IC50 = 3.2 µM) and stimulates TRAIL-mediated apoptosis in glioma cells via ER stress
Formal name: 4S-methyl-salinomycin, monosodium salt
Synonyms: 4-Methylsalinomycin|Monteban|Narasin A
Molecular weight: 787
CAS: 58331-17-2
Purity: ≥98%
Formulation: A solid
Product Type|Biochemicals|Antibiotics|Ionophores||Product Type|Biochemicals|Kinase Inhibitors||Product Type|Biochemicals|Small Molecule Inhibitors|Kinases||Product Type|Biochemicals|Small Molecule Inhibitors|TNF-α/NF-κB Signaling||Research Area|Cancer|Cell Death|Apoptosis||Research Area|Cancer|Cell Signaling|NF-κB Signaling||Research Area|Cell Biology|Cell Signaling|NF-κB Signaling||Research Area|Epigenetics, Transcription, & Translation|Transcription Factors||Research Area|Immunology & Inflammation|Innate Immunity||Research Area|Infectious Disease|Parasitic Diseases
