Description
Nampt is a 52 kDa adipokine secreted by adipose tissue that is involved in the biosynthesis of nicotinamide adenine dinucleotide (NAD+). Two forms of Nampt exist, an intracellular form (iNampt) and an extracellular form (eNampt). While the function of iNampt as an essential and rate-limiting NAD+ biosynthetic enzyme is well established, the physiological role of eNampt is still a matter of debate. Nampt has various functions, including the promotion of vascular smooth muscle cell maturation and inhibition of neutrophil apoptosis. It activates the insulin receptor and has insulin-mimetic effects, lowering blood glucose and improving insulin sensitivity. The protein is highly expressed in visceral fat and serum levels of the protein correlate with obesity.
Synonyms: Nicotinamide Phosphoribosyltransferase|PBEF1|Pre-B Cell Colony Enhancing Factor 1|Visfatin
Immunogen: recombinant human Nampt
Formulation: A 1 mg/ml solution in PBS, pH 7.4
Isotype: IgG2aκ
Applications: ELISA, FC, ICC, IHC, IP, and WB
Origin: Animal/Mouse
Stability: 180 days
Application|ELISA||Application|Flow Cytometry||Application|Immunocytochemistry||Application|Immunohistochemistry||Application|Immunoprecipitation||Application|Western Blot||Product Type|Antibodies|Monoclonal Antibodies||Research Area|Endocrinology & Metabolism|Metabolic Diseases|Obesity
