Blocks ergosterol biosynthesis in fungi by inhibiting squalene epoxidase (Ki = 1.1 µM for C. albicans epoxidase)

Naftifine (hydrochloride) – 1 g

Brand:
Cayman
CAS:
65473-14-5
Storage:
-20
UN-No:
Non-Hazardous - /

Naftifine is an allylamine compound that blocks ergosterol biosynthesis in fungi by inhibiting squalene epoxidase (Ki = 1.1 µM for C. albicans epoxidase).{17902}  

 

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Description

Blocks ergosterol biosynthesis in fungi by inhibiting squalene epoxidase (Ki = 1.1 µM for C. albicans epoxidase)

Formal name: N-methyl-N-[(2E)-3-phenyl-2-propen-1-yl]-1-naphthalenemethanamine, monohydrochloride

Synonyms:  AW 105-843

Molecular weight: 323.9

CAS: 65473-14-5

Purity: ≥98%

Formulation: A crystalline solid

Product Type|Biochemicals|Antifungals|Allylamines||Product Type|Biochemicals|Small Molecule Inhibitors|Sterol Biosynthesis||Research Area|Immunology & Inflammation||Research Area|Infectious Disease|Fungal Diseases

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