An inhibitor of α-synuclein-induced toxicity; prevents α-synuclein-induced defects in Rsp5-dependent endocytosis and vacuolar delivery of Mup1

NAB 2 – 5 mg

Brand:
Cayman
CAS:
1504588-00-4
Storage:
-20
UN-No:
Non-Hazardous - /

NAB 2 is an inhibitor of α-synuclein-induced toxicity.{46118} It prevents α-synuclein-induced defects in Rsp5-dependent endocytosis and vacuolar delivery of Mup1, Golgi-to-vacuole trafficking of Sna3, and degradation of Bap2 in wild-type yeast cells. NAB 2 also prevents formation of α-synuclein foci in wild-type yeast cells, an effect that is prevented by the rsp5G747E point mutation.  

 

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SKU: 26145 - 5 mg Category:

Description

An inhibitor of α-synuclein-induced toxicity; prevents α-synuclein-induced defects in Rsp5-dependent endocytosis and vacuolar delivery of Mup1, Golgi-to-vacuole trafficking of Sna3, and degradation of Bap2 in wild-type yeast cells; prevents formation of α-synuclein foci in wild-type yeast cells,

Formal name: N-[(2-chlorophenyl)methyl]-1-(2,5-dimethylphenyl)-1H-benzimidazole-5-carboxamide

Synonyms: 

Molecular weight: 389.9

CAS: 1504588-00-4

Purity: ≥98%

Formulation: A crystalline solid

Product Type|Biochemicals||Research Area|Neuroscience

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