An adenosine analog; inhibits epinephrine-induced contraction of isolated guinea pig ileum and thoracic aorta at 10 μM; decreases arterial blood pressure and renal blood flow and increases peripheral resistance in anesthetized dogs at 1 mg/kg; inhibits tumor growth in the C3H/ST and C3HB/ST mouse models of spontaneous mammary adenocarcinomas; the most prevelant mRNA modification in eukaryotes and has roles in cell viability and development

N6-Methyladenosine – 1 g

Brand:
Cayman
CAS:
1867-73-8
Storage:
-20
UN-No:
Non-Hazardous - /

N6-Methyladenosine is an adenosine analog.{48666} It inhibits epinephrine-induced contraction of isolated guinea pig ileum and thoracic aorta when used at a concentration of 10 μM. N6-Methyladenosine (1 mg/kg, i.v.) decreases arterial blood pressure and renal blood flow and increases peripheral resistance in anesthetized dogs.{48667} It also inhibits tumor growth in the C3H/ST and C3HB/ST mouse models of spontaneous mammary adenocarcinomas.{48668} N6-Methyladenosine is also the most prevelant mRNA modification in eukaryotes and has roles in cell viability and development.{35631}  

 

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SKU: 28833 - 1 g Category:

Description

An adenosine analog; inhibits epinephrine-induced contraction of isolated guinea pig ileum and thoracic aorta at 10 μM; decreases arterial blood pressure and renal blood flow and increases peripheral resistance in anesthetized dogs at 1 mg/kg; inhibits tumor growth in the C3H/ST and C3HB/ST mouse models of spontaneous mammary adenocarcinomas; the most prevelant mRNA modification in eukaryotes and has roles in cell viability and development

Formal name: N-methyl-adenosine

Synonyms:  NSC 29409

Molecular weight: 281.3

CAS: 1867-73-8

Purity: ≥95%

Formulation: A crystalline solid

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