An adenosine A1 and A3 receptor agonist; binds selectively to rat adenosine A1 and human adenosine A3 receptors over rat adenosine A2A and A3 receptors (Kis = 4.9

N6-Ethyladenosine – 5 mg

Brand:
Cayman
CAS:
14357-08-5
Storage:
-20
UN-No:
Non-Hazardous - /

N6-Ethyladenosine is an adenosine A1 and A3 receptor agonist.{48610} It binds selectively to rat adenosine A1 and human adenosine A3 receptors over rat adenosine A2A and A3 receptors (Kis = 4.9, 4.7, 8,900 and 1,050 nM, respectively, for the recombinant receptors in CHO cells). N6-Ethyladenosine completely inhibits forskolin-induced cAMP accumulation in CHO cells expressing the human recombinant adenosine A3 receptor when used at a concentration of 10 µM.  

 

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SKU: 28428 - 5 mg Category:

Description

An adenosine A1 and A3 receptor agonist; binds selectively to rat adenosine A1 and human adenosine A3 receptors over rat adenosine A2A and A3 receptors (Kis = 4.9, 4.7, 8,900 and 1,050 nM, respectively, for the recombinant receptors in CHO cells); inhibits forskolin-induced cAMP accumulation in CHO cells expressing the human recombinant adenosine A3 receptor at 10 µM

Formal name: N-ethyl-adenosine

Synonyms:  NSC 516603

Molecular weight: 295.3

CAS: 14357-08-5

Purity: ≥98%

Formulation: A solid

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