A selective agonist at A1R (Kis = 2.3

N6-Cyclopentyladenosine – 50 mg

Brand:
Cayman
CAS:
41552-82-3
Storage:
-20
UN-No:
Non-Hazardous - /

N6-Cyclopentyladenosine is a selective agonist at adenosine 1 receptors (A1Rs) (Kis = 2.3, 790, and 43 nM for A1R, A2R, and A3R receptors, respectively, in transfected CHO cells).{34118,27925} When microinjected into the rat brainstem, it increases blood pressure and heart rate.{34115} It is effective for pain in normal and nerve-injured rats and shows anticonvulsant activity in a rat model of generalized seizures.{34116,34117}  

 

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Description

A selective agonist at A1R (Kis = 2.3, 790, and 43 nM for A1R, A2R, and A3R receptors, respectively)

Formal name: N-cyclopentyl-adenosine

Synonyms:  CPA|UK 80882

Molecular weight: 335.4

CAS: 41552-82-3

Purity: ≥99%

Formulation: A solid

Product Type|Biochemicals|Receptor Pharmacology|Agonists||Research Area|Cardiovascular System|Cardiovascular Diseases|Hypertension||Research Area|Cardiovascular System|Heart|Arrhythmia||Research Area|Neuroscience|Pain Research||Research Area|Neuroscience|Seizure Disorders

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