A monoacetylated derivative of spermine (Item No. 18041)

N1-Acetylspermine (hydrochloride) – 50 mg

Brand:
Cayman
CAS:
77928-70-2
Storage:
-20
UN-No:
Non-Hazardous - /

N1-Acetylspermine is a monoacetylated derivative of spermine (Item No. 18041), an endogenous polyamine synthesized from spermidine (Item No. 14918), that displays lower Km and higher Vmax values than spermine, making it a better substrate of polyamine oxidase than the non-acetylated polyamine.{29261} Spermine is required for eukaryotic cell growth and protein synthesis and is involved in the modulation of calcium-dependent immune processes.{27553,29231} N1-Acetylspermine has been used to study the uptake of the anticancer polyamine analog bleomycin-A5 by the human carnitine transporter SLC22A16.{29262}  

 

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Description

A monoacetylated derivative of spermine (Item No. 18041), an endogenous polyamine synthesized from spermidine (Item No. 14918), that displays lower Km and higher Vmax values than spermine, making it a better substrate of polyamine oxidase than the non-acetylated polyamine

Formal name: N-[3-[[4-[(3-aminopropyl)amino]butyl]amino]propyl]-acetamide, trihydrochloride

Synonyms: 

Molecular weight: 353.8

CAS: 77928-70-2

Purity: ≥95%

Formulation: A crystalline solid

Product Type|Biochemicals|Labeling & Detection|Enzyme Substrates||Research Area|Cancer

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