A substrate for polyamine oxidase that is oxidized to 3-acetamidopropanal and putrescine

N1-Acetylspermidine (hydrochloride) – 10 mg

Brand:
Cayman
CAS:
34450-16-3
Storage:
-20
UN-No:
Non-Hazardous - /

N1-Acetylspermidine is an acetyl derivative of spermidine (Item No. 14918) that acts as a substrate for polyamine oxidase (PAO).{26260} In peroxisomes, PAO oxidizes N1-acetylspermidine to 3-acetamidopropanal and putrescine, a positively charged polyamine that binds DNA and is involved in various cellular processes including cell division, differentiation, and membrane function.{26259,23742,23743,12989} N1-Acetylspermidine has been used to examine the interaction between DNA and polyamines during the cleavage of phosphodiester bonds at apurinic/apyrimidinic sites in DNA.{27034}  

 

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SKU: 9001535 - 10 mg Category:

Description

A substrate for polyamine oxidase that is oxidized to 3-acetamidopropanal and putrescine, a polyamine involved in the division, differentiation, and membrane function of cells; used to examine the interaction between DNA and polyamines during the cleavage of phosphodiester bonds at apurinic/apyrimidinic sites in DNA

Formal name: N-[3-[(4-aminobutyl)amino]propyl]-acetamide, dihydrochloride

Synonyms:  N1-AcSPD

Molecular weight: 260.2

CAS: 34450-16-3

Purity: ≥98%

Formulation: A crystalline solid

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