A phenolic amide with diverse biological activities; decreases NO production (IC50 = 17.36 µM) and iNOS activity and increases NO scavenging without inducing cytotoxicity in LPS-stimulated BV-2 cells; scavenges DPPH radicals in cell-free assays; inhibits proliferation of HeLa and L929 cells by 72.2 and 22%

N-trans-Feruloyltyramine – 5 mg

Brand:
Cayman
CAS:
66648-43-9
Storage:
-20
UN-No:
De Minimis - 3077 / 9

N-trans-Feruloyltyramine is a phenolic amide originally isolated from S. melongena that has diverse biological activities, including anti-inflammatory, antioxidative, and antiproliferative properties.{45249} It decreases nitric oxide (NO) production (IC50 = 17.36 µM) and inducible NO synthase (iNOS) activity and increases NO scavenging without inducing cytotoxicity in LPS-stimulated BV-2 cells.{45250} It also scavenges 2,2-diphenyl-1-picrylhydrazyl (DPPH; Item No. 14805) radicals in TLC autographic and spectrophotometric assays.{45251} N-trans-Feruloyltyramine inhibits proliferation of HeLa and L929 cells by 72.2 and 22%, respectively, when used at a concentration of 30 µg/ml.{45252}  

 

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SKU: 27459 - 5 mg Category:

Description

A phenolic amide with diverse biological activities; decreases NO production (IC50 = 17.36 µM) and iNOS activity and increases NO scavenging without inducing cytotoxicity in LPS-stimulated BV-2 cells; scavenges DPPH radicals in cell-free assays; inhibits proliferation of HeLa and L929 cells by 72.2 and 22%, respectively, at 30 µg/ml

Formal name: (2E)-3-(4-hydroxy-3-methoxyphenyl)-N-[2-(4-hydroxyphenyl)ethyl]-2-propenamide

Synonyms:  (E)-Feruloyltyramine|Alfrutamide|Moupinamide

Molecular weight: 313.4

CAS: 66648-43-9

Purity: ≥98%

Formulation: A crystalline solid

Product Type|Biochemicals|Natural Products|Polyphenols||Product Type|Biochemicals|Ox Stress Reagents|Antioxidants||Research Area|Cancer||Research Area|Immunology & Inflammation||Research Area|Oxidative Stress & Reactive Species|Antioxidant Activity||Research Area|Oxidative Stress & Reactive Species|Reactive Nitrogen|iNOS||Research Area|Oxidative Stress & Reactive Species|Reactive Oxygen|Non-enzymatic

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