A cell permeable spin trap commonly used in free radical research that protects against oxidative damage caused by various inflammatory events

N-tert-butyl-α-Phenylnitrone – 1 g

Brand:
Cayman
CAS:
3376-24-7
Storage:
-20
UN-No:
Non-Hazardous - /

N-tert-butyl-α-Phenylnitrone (PBN) is a cell permeable spin trap commonly used in free radical research.{9996} It protects against oxidative damage caused by various inflammatory events, demonstrating neuroprotective, anti-anging, and antidiabetic effects.{9453} At millimolar concentrations, PBN has been shown to inhibit LPS-induced NF-κB DNA binding activity and inhibits COX-2 catalytic activity.{7405}  

 

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Description

A cell permeable spin trap commonly used in free radical research that protects against oxidative damage caused by various inflammatory events, demonstrating neuroprotective, anti-anging, and antidiabetic effects

Formal name: 2-methyl-N-(phenylmethylene)-2-propanamine N-oxide

Synonyms:  PBN

Molecular weight: 177.3

CAS: 3376-24-7

Purity: ≥98%

Formulation: A crystalline solid

Product Type|Biochemicals|Ox Stress Reagents|Spin Traps||Research Area|Immunology & Inflammation|Inflammatory Lipid Mediators|Prostaglandins||Research Area|Immunology & Inflammation|Innate Immunity||Research Area|Oxidative Stress & Reactive Species|Antioxidant Activity

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