A colorimetric thrombin substrate; cleavage of the GPR peptide sequence releases pNA

N-(p-Tosyl)-GPR-pNA (acetate) – 250 mg

Brand:
Cayman
CAS:
86890-95-1
Storage:
-20
UN-No:
Non-Hazardous - /

N-(p-Tosyl)-GPR-pNA is a colorimetric substrate for thrombin.{48594} Thrombin preferentially binds to and cleaves the Gly-Pro-Arg (GPR) peptide sequence to release p-nitroanilide (pNA), which can be quantified by colorimetric detection at 405 nm as a measure of thrombin activity.  

 

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SKU: 27568 - 250 mg Category:

Description

A colorimetric thrombin substrate; cleavage of the GPR peptide sequence releases pNA, which can be quantified by colorimetric detection at 405 nm as a measure of thrombin activity

Formal name: N-[(4-methylphenyl)sulfonyl]glycyl-L-prolyl-N-(4-nitrophenyl)-L-argininamide, monoacetate

Synonyms:  N-(p-Tosyl)-Gly-Pro-Arg-p-Nitroanilide|Tos-Gly-Pro-Arg-pNA

Molecular weight: 662.7

CAS: 86890-95-1

Purity: ≥98%

Formulation: A solid

Application|Enzyme Activity||Product Type|Biochemicals|Labeling & Detection|Dyes, Stains, & Indicators||Product Type|Biochemicals|Labeling & Detection|Enzyme Substrates||Research Area|Cell Biology|Proteolysis|Cytosolic & Secreted Proteases

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