The immediate precursor of melatonin that is produced from serotonin by the enzyme aralkylamine N-acetyltransferase and converted to melatonin by acetylserotonin O-methyltransferase; acts as an agonist at the melatonin receptors MT1

N-Acetylserotonin – 50 mg

Brand:
Cayman
CAS:
1210-83-9
Storage:
-20
UN-No:
Non-Hazardous - /

N-Acetylserotonin (NAS) is the immediate precursor of melatonin (Item No. 14427). It is produced from serotonin by the enzyme aralkylamine N-acetyltransferase and is converted to melatonin by acetylserotonin O-methyltransferase.{23138} Like melatonin, NAS is considered to be a neurotransmitter and acts as an agonist at the melatonin receptors MT1, MT2, and MT3.{23139} NAS may also have unique central effects since it is distributed in specific brain areas separate from serotonin and melatonin.{23139}  

 

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Description

The immediate precursor of melatonin that is produced from serotonin by the enzyme aralkylamine N-acetyltransferase and converted to melatonin by acetylserotonin O-methyltransferase; acts as an agonist at the melatonin receptors MT1, MT2, and MT3

Formal name: N-[2-(5-hydroxy-1H-indol-3-yl)ethyl]-acetamide

Synonyms:  N-Acetyl-5-hydroxytryptamine|NAS

Molecular weight: 218.3

CAS: 1210-83-9

Purity: ≥98%

Formulation: A crystalline solid

Product Type|Biochemicals|Receptor Pharmacology|Agonists||Research Area|Neuroscience

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