A structural analog of melatonin that binds the melatonin MT2 receptor (Ki = 41 nM); acts as a melatonin receptor antagonist in frog skin and chicken retina and as a partial agonist in rabbit retina

N-acetyl Tryptamine – 25 mg

Brand:
Cayman
CAS:
1016-47-3
Storage:
-20
UN-No:
Non-Hazardous - /

N-acetyl Tryptamine is a structural analog of melatonin (5-methoxy-N-acetyltryptamine; Item No. 14427) that binds the melatonin MT2 receptor (Ki = 41 nM).{30340} It acts as a melatonin receptor antagonist in frog skin and chicken retina and as a partial agonist in rabbit retina.{30338,30339,26017} N-acetyl Tryptamine is also a reaction product of assays for serotonin N-acetyltransferase, the penultimate enzyme in the melatonin biosynthetic pathway.{30337}  

 

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Description

A structural analog of melatonin that binds the melatonin MT2 receptor (Ki = 41 nM); acts as a melatonin receptor antagonist in frog skin and chicken retina and as a partial agonist in rabbit retina

Formal name: N-[2-(1H-indol-3-yl)ethyl]-acetamide

Synonyms: 

Molecular weight: 202.3

CAS: 1016-47-3

Purity: ≥98%

Formulation: A crystalline solid

Product Type|Biochemicals|Receptor Pharmacology|Agonists||Product Type|Biochemicals|Receptor Pharmacology|Antagonists||Research Area|Neuroscience|Behavioral Neuroscience|Sleep & Biological Rhythms

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