An esterified form of NAC; has enhanced cell permeability compared to NAC in isolated perfused rat liver; prevents tert-butyl hydroperoxide-induced formation of methemoglobin in isolated human red blood cells at 1 mM; increases glutathione levels in rat liver

N-acetyl-L-Cysteine ethyl ester – 100 mg

Brand:
Cayman
CAS:
59587-09-6
Storage:
-20
UN-No:
Non-Hazardous - /

N-acetyl-L-Cysteine ethyl ester is an esterified form of N-acetyl-L-cysteine (NAC; Item No. 20261). It has enhanced cell permeability in isolated perfused rat liver compared to NAC.{53848} N-acetyl-L-Cysteine ethyl ester (1 mM) prevents tert-butyl hydroperoxide-induced formation of methemoglobin in isolated human red blood cells. It increases glutathione levels in rat liver, kidney, heart, testis, and brain when administered at a dose of 50 mg/kg twice per day for two weeks. N-acetyl-L-Cysteine ethyl ester reduces increases in plasma aspartate aminotransferase (AST), alanine aminotransferase (ALT), and lactate dehydrogenase (LDH) levels induced by paracetamol (acetaminophen; Item No. 10024) in rats.  

 

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SKU: 30299 - 100 mg Category:

Description

An esterified form of NAC; has enhanced cell permeability compared to NAC in isolated perfused rat liver; prevents tert-butyl hydroperoxide-induced formation of methemoglobin in isolated human red blood cells at 1 mM; increases glutathione levels in rat liver, kidney, heart, testis, and brain at 50 mg/kg twice per day; reduces acetaminophen-induced increases in plasma AST, ALT, and LDH levels in rats ,,

Formal name:

Synonyms:  NAC ethyl ester|NACET

Molecular weight: 191.2

CAS: 59587-09-6

Purity: ≥95%

Formulation: A crystalline solid

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