Description
An antioxidant; amide form of NAC; has increased cellular membrane and blood-brain barrier permeability compared to NAC; inhibits glutamate-induced cytotoxicity, decreases in intracellular GSH levels, and increases in intracellular ROS levels in PC12 cells at 750 μM; reduces cortical tissue damage and decreases the distance traveled to the platform in the Morris water maze in a rat model of traumatic brain injury; inhibits ovalbumin-induced decreases in GSH, increases in nuclear NF-κB p65 and HIF-1α, and increases in IL-4, IL-5, and IL-13 levels in mouse lung tissue at 60 and 120 mg/kg
Formal name: (2R)-2-(acetylamino)-3-mercapto-propanamide
Synonyms: NACA|N-Acetylcysteine amide
Molecular weight: 162.2
CAS: 38520-57-9
Purity: ≥95%
Formulation: A crystalline solid
Product Type|Biochemicals|Ox Stress Reagents|Antioxidants||Research Area|Cell Biology|Cell Signaling|NF-κB Signaling||Research Area|Epigenetics, Transcription, & Translation|Transcription Factors||Research Area|Immunology & Inflammation||Research Area|Neuroscience|Behavioral Neuroscience|Learning & Memory||Research Area|Neuroscience|Neuroprotection||Research Area|Oxidative Stress & Reactive Species|Antioxidant Activity||Research Area|Oxidative Stress & Reactive Species|Reactive Sulfur|Glutathione
