An antioxidant and precursor of glutathione that scavenges H2O2

N-acetyl-L-Cysteine – 25 g

Brand:
Cayman
CAS:
616-91-1
Storage:
-20
UN-No:
Non-Hazardous - /

N-Acetyl-L-cysteine (NAC) is an antioxidant and precursor of glutathione that has multiple effects in cells and animals. As an antioxidant, NAC scavenges hydrogen peroxide, hydroxyl radical, and hypochlorous acid.{32379,32381} NAC may be deacetylated to cysteine, which can be combined with glutamate and glycine to produce reduced glutathione (Item No. 10007461), which serves to reduce hydroperoxides and detoxify xenobiotics.{32379,32381} The free sulfhydryl group of NAC can also hydrolyze disulfide bonds of mucins and other proteins, thus facilitating clearance of mucus.{32384} Through these actions, NAC inhibits DNA adduct formation, limits hepatotoxic effects of acetaminophen, and provides diverse cytoprotective effects in vivo.{32378,32379,32380,32381,32384,32385}  

 

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Description

An antioxidant and precursor of glutathione that scavenges H2O2, •OH, and HOCl; deacetylated to cysteine, which can be combined with glutamate and glycine to produce reduced glutathione; hydrolyzes disulfide bonds of mucins and other proteins

Formal name: N-acetyl-L-cysteine

Synonyms:  Acetylcysteine|NAC|NSC 111180

Molecular weight: 163.2

CAS: 616-91-1

Purity: ≥95%

Formulation: A crystalline solid

Product Type|Biochemicals|Ox Stress Reagents|Antioxidants||Research Area|Oxidative Stress & Reactive Species|Antioxidant Activity||Research Area|Oxidative Stress & Reactive Species|DNA/RNA Oxidative Damage||Research Area|Oxidative Stress & Reactive Species|Reactive Oxygen

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