A fluorescent probe; used as a precursor for protection of amine groups; used to detect nucleic acids and their precursors

N-(2-hydroxyethyl)-Naphthalimide – 5 g

Brand:
Cayman
CAS:
5450-40-8
Storage:
-20
UN-No:
Non-Hazardous - /

N-(2-hydroxyethyl)-Naphthalimide is an N-substituted 1,8-naphthalimide used as a fluorescent probe and as a precursor for protection of amine groups.{28744} It is used to detect nucleic acids and their precursors, which quench the fluorescence of N-(2-hydroxyethyl)-naphthalimide.{41257} Nucleic acids quench the fluorescence most strongly followed by nucleosides and nucleobases, of which purine bases quench more strongly than pyrimidine bases. N-(2-hydroxyethyl)-Naphthalimide is electroactive and forms adducts with 1,3-dihydroxy benzene and 1,3,5-trihydroxybenzene.{28744} N-(2-hydroxyethyl)-Naphthalimide displays excitation spectra of 330-333 and 344-347 nm with emission spectra of 366-378 nm in solvents of varying polarities, with a higher Stokes shift in less polar solvents.{41256}  

 

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Description

A fluorescent probe; used as a precursor for protection of amine groups; used to detect nucleic acids and their precursors, which quench its fluorescence; is electroactive; ex/em = 330-333 and 344-347/366-378 nm in solvents of varying polarities

Formal name: 2-(2-hydroxyethyl)-1H-benz[de]isoquinoline-1,3(2H)-dione

Synonyms:  N-(2-hydroxyethyl)-1,8-Naphthalimide|NSC 11547

Molecular weight: 241.2

CAS: 5450-40-8

Purity: ≥95%

Formulation: A crystalline solid

Application|Fluorescence||Product Type|Biochemicals|Labeling & Detection|Fluorescent Probes||Research Area|Epigenetics, Transcription, & Translation|RNA, DNA, & Protein Synthesis

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