A form of the 14-carbon myristic acid with an ω-terminal alkyne group; can be used in linking reactions utilizing click chemistry

Myristic Acid Alkyne – 5 mg

Brand:
Cayman
CAS:
82909-47-5
Storage:
-20
UN-No:
De Minimis - 1170 / 3

Myristic acid is a 14-carbon saturated (14:0) fatty acid. In vivo, it is commonly added covalently to the N-terminus of proteins in a co-translational process termed N-myristoylation.{17231} The sirtuin SIRT6 removes this acyl group from myristoylated TNF-α, enhancing secretion.{22694} Myristic acid alkyne is a form of this myristic acid (Item No. 13351) with an ω-terminal alkyne. Such terminal alkyne groups can be used in linking reactions, known as click chemistry, characterized by high dependability and specificity of azide-alkyne bioconjugation reactions.{17991,17992} Click chemistry has only recently been applied to the study of lipids.{22694,16188}  

 

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Description

A form of the 14-carbon myristic acid with an ω-terminal alkyne group; can be used in linking reactions utilizing click chemistry

Formal name: 13-tetradecynoic acid

Synonyms:  13-alkyne Myristic Acid|Alk-12|Click Tag™ Myristic Acid

Molecular weight: 224.3

CAS: 82909-47-5

Purity: ≥98%

Formulation: A solution in ethanol

Application|Click Chemistry||Product Type|Biochemicals|Lipids|Fatty Acids||Research Area|Lipid Biochemistry|Fatty Acids||Research Area|Lipid Biochemistry|Protein Lipidation

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