A trisubstituted purine which binds microtubules

Myoseverin – 1 mg

Brand:
Cayman
CAS:
267402-71-1
Storage:
-20
UN-No:
Non-Hazardous - /

Myoseverin is a trisubstituted purine which binds microtubules, reversibly altering cellular function.{23401,23402} At 20 μM, it directly binds tubulin and disrupts the structure of the microtubule cytoskeleton, resulting in myotube fission.{23401} Myoseverin arrests cell cycle in the G2/M phase, followed by DNA synthesis and cell proliferation after removal of the compound.{23401}  

 

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Description

A trisubstituted purine which binds microtubules, reversibly altering cellular function; it directly binds tubulin, disrupts the structure of the microtubule cytoskeleton, and arrests cell cycle in the G2/M phase

Formal name: N2,N6-bis[(4-methoxyphenyl)methyl]-9-(1-methylethyl)-9H-purine-2,6-diamine

Synonyms: 

Molecular weight: 432.5

CAS: 267402-71-1

Purity: ≥98%

Formulation: A crystalline solid

Product Type|Biochemicals|Microtubule Dynamics||Research Area|Cell Biology|Cell Cycle||Research Area|Cell Biology|Cytoskeleton & Motor Proteins

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