A prodrug form of mycophenolic acid; increases duration of transplant motor activity in a rabbit model of retroperitoneal heterotopic heart transplantation at 12.5 mg/kg; eliminates formation of microbleeds and hemorrhages in the cerebrum of stroke-prone spontaneously hypertensive rats; lowers MAP and reduces urinary albumin excretion and glomerulosclerosis

Mycophenolate Mofetil – 500 mg

Brand:
Cayman
CAS:
128794-94-5
Storage:
-20
UN-No:
Non-Hazardous - /

Mycophenolate mofetil is a prodrug form of mycophenolic acid (Item No. 21716).{37581,37582,37583} In vivo, mycophenolate mofetil (12.5 mg/kg) increases duration of transplant motor activity in a rabbit model of retroperitoneal heterotopic heart transplantation.{37581} It eliminates formation of microbleeds and hemorrhages in the cerebrum of stroke-prone spontaneously hypertensive rats.{37582} Mycophenolate mofetil also lowers mean arterial pressure (MAP) and reduces urinary albumin excretion and glomerulosclerosis, markers of renal damage, in a mouse model of systemic lupus erythematosus (SLE).{37583}  

 

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Description

A prodrug form of mycophenolic acid; increases duration of transplant motor activity in a rabbit model of retroperitoneal heterotopic heart transplantation at 12.5 mg/kg; eliminates formation of microbleeds and hemorrhages in the cerebrum of stroke-prone spontaneously hypertensive rats; lowers MAP and reduces urinary albumin excretion and glomerulosclerosis, markers of renal damage, in a mouse model of SLE

Formal name: 6-(1,3-dihydro-4-hydroxy-6-methoxy-7-methyl-3-oxo-5-isobenzofuranyl)-4-methyl-4E-hexenoic acid, 2-(4-morpholinyl)ethyl ester

Synonyms:  MMF|RS 61443

Molecular weight: 433.5

CAS: 128794-94-5

Purity: ≥95%

Formulation: A crystalline solid

Product Type|Biochemicals||Research Area|Immunology & Inflammation|Autoimmunity|Lupus

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