A fungal metabolite with anticancer and antimicrobial activities; cytotoxic to DLD-1

Myceliothermophin E – 1 mg

Brand:
Cayman
CAS:
955083-90-6
Storage:
-20
UN-No:
Non-Hazardous - /

Myceliothermophin E is a polyketide-amino acid hybrid fungal metabolite that has been found in T. thermophilus and has anticancer and antimicrobial activities.{46920,46921} It is cytotoxic to DLD-1, Hep3B, HepG2, and HGC-27 cancer cells (IC50s = 0.32, 0.42, 0.26, and 0.08 μg/ml, respectively).{46920} Myceliothermophin E is active against methicillin-resistant, but not -sensitive, S. aureus (MICs = 15.8 and >100 μM, respectively).{46921}  

 

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SKU: 30053 - 1 mg Category:

Description

A fungal metabolite with anticancer and antimicrobial activities; cytotoxic to DLD-1, Hep3B, HepG2, and HGC-27 cancer cells (IC50s = 0.32, 0.42, 0.26, and 0.08 μg/ml, respectively); active against methicillin-resistant, but not -sensitive, S. aureus (MICs = 15.8 and >100 μM, respectively)

Formal name: (5Z)-1,5-dihydro-5-(2-methylpropylidene)-3-[[(1S,2R,4aR,6R,8aS)-1,2,4a,5,6,7,8,8a-octahydro-3,4a,6-trimethyl-2-[(1E)-1-methyl-1-propen-1-yl]-1-naphthalenyl]carbonyl]-2H-pyrrol-2-one

Synonyms: 

Molecular weight: 395.6

CAS: 955083-90-6

Purity: ≥70%

Formulation: A solid

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