An odoriferous component of musk that has been shown to exhibit anti-inflammatory effects by reducing the expression of proinflammatory cytokines both in vitro and in vivo; also reported to be both cardioprotective and neuroprotective during conditions of ischemia and to promote proliferation and differentiation of neural stem cells

Muscone – 1 g

Brand:
Cayman
CAS:
541-91-3
Storage:
-20
UN-No:
Limited Quantity - 1170 / 3

(±)-Muscone is an odoriferous constituent of musk, a glandular secretion originally collected from the male musk deer, that has found use both in the composition of perfumes and in traditional Chinese medicine practices.{26138} (±)-Muscone has been shown to exhibit anti-inflammatory effects by reducing the expression of proinflammatory cytokines both in vitro and in vivo. In a model of vertebral end-plate degeneration, 25 µM (±)-muscone was shown to reverse IL-1β-induced upregulation of IL-1β, TNF-α, cyclooxygenase 2, inducible nitric oxide synthase, matrix metalloproteinase 13, aggrecanase 2, and nitric oxide.{26139} It has also been reported to be both cardioprotective and neuroprotective during conditions of ischemia and to promote proliferation and differentiation of neural stem cells.{26142,26140,26141}  

 

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Description

An odoriferous component of musk that has been shown to exhibit anti-inflammatory effects by reducing the expression of proinflammatory cytokines both in vitro and in vivo; also reported to be both cardioprotective and neuroprotective during conditions of ischemia and to promote proliferation and differentiation of neural stem cells

Formal name: 3-methyl-cyclopentadecanone

Synonyms:  3-Methylcyclopentadecanone

Molecular weight: 238.4

CAS: 541-91-3

Purity: ≥98%

Formulation: A solution in ethanol

Product Type|Biochemicals|Natural Products||Research Area|Cardiovascular System|Cardiovascular Diseases|Myocardial Infarction||Research Area|Cell Biology|Stem Cell Research|Differentiation||Research Area|Cell Biology|Stem Cell Research|Proliferation||Research Area|Immunology & Inflammation||Research Area|Neuroscience|Neuroprotection|Ischemia

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