A cell-permeable and positively charged tetrazolium dye; used to detect reductive metabolism in cells; taken up by cells through the plasma membrane and then reduced to formazan by intracellular NAD(P)H-oxidoreductases; frequently used in colorimetric assays to measure cell proliferation

MTT – 5 g

Brand:
Cayman
CAS:
298-93-1
Storage:
-20
UN-No:
Non-Hazardous - /

MTT is a cell-permeable and positively charged tetrazolium dye that is used to detect reductive metabolism in cells.{14422} It is taken up by cells through the plasma membrane and then reduced to formazan by intracellular NAD(P)H-oxidoreductases. It is frequently used in colorimetric assays to measure cell proliferation, cytotoxicity, and apoptosis.  

 

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Description

A cell-permeable and positively charged tetrazolium dye; used to detect reductive metabolism in cells; taken up by cells through the plasma membrane and then reduced to formazan by intracellular NAD(P)H-oxidoreductases; frequently used in colorimetric assays to measure cell proliferation, cytotoxicity, and apoptosis

Formal name: 2-(4,5-dimethyl-2-thiazolyl)-3,5-diphenyl-2H-tetrazolium, monobromide

Synonyms:  Methylthialazole Tetrazolium|NSC 60102|Thiazolyl Blue|Thiazolyl Blue Tetrazolium Bromide

Molecular weight: 414.3

CAS: 298-93-1

Purity: ≥95%

Formulation: A crystalline solid

Product Type|Biochemicals|Labeling & Detection|Dyes, Stains, & Indicators||Research Area|Cell Biology|Cell Death|Apoptosis

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