Description
A selective inhibitor of Mps1 kinase (IC50 = 367 nM); disrupts the recruitment of Mad2 to kinetochores and increases the frequency of multipolar mitosis in U2OS cells
Formal name: 1-[3-methoxy-4-[[4-[[2-[(1-methylethyl)sulfonyl]phenyl]amino]-1H-pyrrolo[2,3-b]pyridin-6-yl]amino]phenyl]-4-piperidinol
Synonyms: Monopolar Spindle 1 Kinase Inhibitor 1|Mps1 Kinase Inhibitor 1
Molecular weight: 535.7
CAS: 1125593-20-5
Purity: ≥98%
Formulation: A crystalline solid
Product Type|Biochemicals|Kinase Inhibitors|Other Serine/Threonine Kinases||Product Type|Biochemicals|Small Molecule Inhibitors|Kinases||Research Area|Cell Biology|Cytoskeleton & Motor Proteins
