A form of glutamate linked to a photoprotecting that upon exposure to light (300 - 380 nm excitation) releases L-glutamate within submicroseconds; used to investigate the mechanisms of fast synaptic glutamate receptors in situ

MNI-caged-L-glutamate (trifluoroacetate salt) – 25 mg

Brand:
Cayman
CAS:
2226362-29-2
Storage:
-20
UN-No:
Non-Hazardous - /

MNI-caged-L-glutamate is a form of glutamate linked to a 4-methoxy-7-nitroindolinyl (MNI) photoprotecting group that is pharmacologically inactive at neuronal glutamate receptors (up to mM concentrations).{32103} Upon exposure to light (300 – 380 nm excitation), L-glutamate is cleaved of MNI and released within submicroseconds.{32103} This compound can be used to investigate the mechanisms of fast synaptic glutamate receptors in situ.  

 

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Description

A form of glutamate linked to a photoprotecting that upon exposure to light (300 – 380 nm excitation) releases L-glutamate within submicroseconds; used to investigate the mechanisms of fast synaptic glutamate receptors in situ

Formal name: (αS)-α-amino-2,3-dihydro-4-methoxy-7-nitro-δ-oxo-1H-indole-1-pentanoic acid, 2,2,2-trifluoroacetate

Synonyms: 

Molecular weight: 437.3

CAS: 2226362-29-2

Purity: ≥95%

Formulation: A crystalline solid

Product Type|Biochemicals|Ion Channel Modulation|Activators||Product Type|Biochemicals|Receptor Pharmacology|Agonists||Research Area|Neuroscience

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