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Mn SOD (rat) Polyclonal Antibody – 25 µl

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Cayman
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Superoxide dismutase (SOD) is an endogenously-produced intracellular enzyme present in almost every cell in the body.{15491} It catalyzes the dismutation of the superoxide radical O2- to O2 and H2O2.{15490,15493} There are two main types of SOD in mammalian cells. One form, SOD1, contains Cu and Zn ions as a homodimer and exists in the cytoplasm. The two subunits of 16 kDa each are linked by two cystines forming an intra-subunit disulphide bridge.{15491} The second form, SOD2, is a manganese-containing enzyme and resides in the mitochondrial matrix. It is a homotetramer of 80 kDa. The third form, SOD3 or EC-SOD, is like SOD1 in that it contains Cu and Zn ions, however it is distinct in that it is a homotetramer, with a mass of 30 kDa and it exists only in the extra-cellular space.{15494} SOD3 can also be distinguished by its heparin-binding capacity.{15489}  

 

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SKU: 10011389 - 25 µl Category:

Description

Antigen: rat Mn SOD • Host: rabbit • Cross-reactivity: (+) human, rat, mouse, bovine, canine, chicken, Drosophila, guinea pig, porcine, hamster, monkey, rabbit, sheep, and Xenopus Mn SOD • Applications: WB, IP, IHC, and EIA • SOD2 is a manganese-containing enzyme in the mitochondrial matrix that catalyzes the dismutation of the superoxide radical O2- to O2 and H2O2.

Synonyms: Manganese Superoxide Dismutase

Immunogen: rat Mn SOD

Formulation: affinity-purified antibody at 1 mg/ml in PBS, pH 7.0, containing 50% glycerol and 0.1% sodium azide

Isotype:

Applications: WB, IP, IHC, and ELISA

Origin: Animal/Rabbit

Stability: 365 days

Application|ELISA||Application|Immunohistochemistry||Application|Immunoprecipitation||Application|Western Blot||Product Type|Antibodies|Polyclonal Antibodies||Research Area|Oxidative Stress & Reactive Species|Reactive Oxygen|Superoxide Dismutase

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