An auristatin with anticancer activity; cytotoxic to Karpas 299 anaplastic large cell lymphoma

MMAF – 10 mg

Brand:
Cayman
CAS:
745017-94-1
Storage:
-20
UN-No:
Non-Hazardous - /

MMAF is an auristatin with anticancer activity.{37315} It is cytotoxic to Karpas 299 anaplastic large cell lymphoma, H3396 breast carcinoma, and 786-O and Caki-1 renal carcinoma cells in vitro (IC50s = 119, 105, 257, and 200 nM, respectively), as well as in a panel of 11 lymphoma cell lines (IC50s = 34.8-164 nM).  

 

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SKU: 30197 - 10 mg Category:

Description

An auristatin with anticancer activity; cytotoxic to Karpas 299 anaplastic large cell lymphoma, H3396 breast carcinoma, and 786-O and Caki-1 renal carcinoma cells in vitro (IC50s = 119, 105, 257, and 200 nM, respectively), as well as in a panel of 11 lymphoma cell lines (IC50s = 34.8-164 nM)

Formal name: N-methyl-L-valyl-L-valyl-(3R,4S,5S)-3-methoxy-5-methyl-4-(methylamino)heptanoyl-(αR,βR,2S)-β-methoxy-α-methyl-2-pyrrolidinepropanoyl-L-phenylalanine

Synonyms:  Monomethylauristatin F

Molecular weight: 732

CAS: 745017-94-1

Purity: ≥95%

Formulation: A solid

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