Potent

(+)-MK-801 (hydrogen maleate) – 50 mg

Brand:
Cayman
CAS:
77086-22-7
Storage:
-20
UN-No:
De Minimis - 2811 / 6.1

MK-801 is a potent, selective and non-competitive N-methyl-D-aspartate (NMDA) (Item No. 14581) receptor antagonist (Ki = 30.5 nM) that acts at the NMDA receptor-operated ion channel as an open channel blocker, preventing Ca2+ flux.{14407} It has been shown to be protective in various models of ischemia as well as to inhibit behavioral sensitization to certain psychostimulants.{14409,14408}  

 

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SKU: 10009019 - 50 mg Category:

Description

Potent, selective and non-competitive NMDA receptor antagonist (Ki = 30.5 nM); acts at the NMDA receptor-operated ion channel as an open channel blocker, preventing Ca2+ flux

Formal name: 10,11-dihydro-5S-methyl-5H-dibenzo[a,d]cyclohepten-5,10-imine, (2Z)-2-butenedioate

Synonyms:  Dizocilpine

Molecular weight: 337.4

CAS: 77086-22-7

Purity: ≥98%

Formulation: A crystalline solid

Product Type|Biochemicals|Ion Channel Modulation|Blockers||Research Area|Neuroscience|Neuroprotection|Ischemia

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