A mitochondria-targeting superoxide dismutase mimetic that reduces mitochondrial O2- to H2O2

MitoTEMPOL – 25 mg

Brand:
Cayman
CAS:
1101113-39-6
Storage:
-20
UN-No:
Non-Hazardous - /

MitoTEMPOL is a mitochondria-targeting superoxide dismutase mimetic that reduces mitochondrial O2- to H2O2.{27263,32303} Like the related compound MitoTEMPO (Item No. 16621), MitoTEMPOL combines an antioxidant moiety (here, TEMPOL, also known as 4-hydroxy-TEMPO) with the lipophilic cation triphenylphosphonium, which allows it to pass through lipid bilayers and accumulate in mitochondria.{27263} MitoTEMPOL has been used to elucidate the role of mitochondria-derived superoxide in mitochondrial, cellular, and whole animal signaling.{32303,32304,32305,32306,32307}  

 

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Description

A mitochondria-targeting superoxide dismutase mimetic that reduces mitochondrial O2- to H2O2

Formal name: 2,2,6,6-tetramethyl-4-[[5-(triphenylphosphonio)pentyl]oxy]-1-piperidinyloxy, monobromide

Synonyms: 

Molecular weight: 583.6

CAS: 1101113-39-6

Purity: ≥98%

Formulation: A solid

Product Type|Biochemicals|Ox Stress Reagents|Antioxidants||Research Area|Cell Biology|Mitochondrial Biology||Research Area|Oxidative Stress & Reactive Species|Antioxidant Activity||Research Area|Oxidative Stress & Reactive Species|Reactive Oxygen|Superoxide Dismutase

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