An oxidized form of mitoquinol; reduced to mitoquinol in isolated bovine heart mitochondrial membranes using succinate for respiration at 50 µM; increases the rate of hydrogen peroxide formation in isolated BAECs at 0.01-10 µM; induces cell death in isolated mouse pancreatic acinar cells at 1 µM; in combination with mitoquinol

Mitoquinone (mesylate) – 25 mg

Brand:
Cayman
CAS:
845959-50-4
Storage:
-20
UN-No:
Non-Hazardous - /

Mitoquinone is an oxidized form of mitoquinol (Item No. 89950).{46636} It is reduced to mitoquinol in isolated bovine heart mitochondrial membranes using succinate for respiration when used at a concentration of 50 µM. Mitoquinone (0.01-10 µM) increases the rate of hydrogen peroxide formation in isolated bovine aortic endothelial cells (BAECs).{46637} It induces cell death in isolated mouse pancreatic acinar cells when used at a concentration of 1 µM.{46638} Mitoquinone, in combination with mitoquinol, reduces malondialdehyde (MDA) levels in isolated rat liver mitochondria and decreases caspase activity in Jurkat cells.{46636}  

 

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SKU: 29317 - 25 mg Category:

Description

An oxidized form of mitoquinol; reduced to mitoquinol in isolated bovine heart mitochondrial membranes using succinate for respiration at 50 µM; increases the rate of hydrogen peroxide formation in isolated BAECs at 0.01-10 µM; induces cell death in isolated mouse pancreatic acinar cells at 1 µM; in combination with mitoquinol, reduces MDA levels in isolated rat liver mitochondria and decreases caspase activity in Jurkat cells

Formal name: [10-(4,5-dimethoxy-2-methyl-3,6-dioxo-1,4-cyclohexadien-1-yl)decyl]triphenyl-phosphonium, monomethanesulfonate

Synonyms: 

Molecular weight: 678.8

CAS: 845959-50-4

Purity: ≥95%

Formulation: A solution in ethanol:water (1:1)

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