A toxin produced by cyanobacteria that inhibits the catalytic activity of protein phosphatases PP1C

Microcystin-RR – 100 µg

Brand:
Cayman
CAS:
111755-37-4
Storage:
-20
UN-No:
De Minimis - 2811 / 6.1

Microcystins are hepatotoxic cyclic heptapeptide toxins produced by cyanobacteria.{13247} They are responsible for periodic poisonings of humans and livestock drinking fresh water where the blue-green algae are endemic. The toxicity of microcystins is initiated by the inhibition of the catalytic activity of protein phosphatase (PP) 1 and PP2A.{14268} Microcystin-RR inhibits PP1C, PP1γ, and PP2A with Ki values of 0.15, 0.24, and 0.018 nM, respectively.{14268}  

 

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SKU: 10007868 - 100 µg Category:

Description

A toxin produced by cyanobacteria that inhibits the catalytic activity of protein phosphatases PP1C, PP1γ, and PP2A with Ki values of 0.15, 0.24, and 0.018 nM, respectively

Formal name: cyclo[2,3-didehydro-N-methylalanyl-D-alanyl-L-arginyl-(3S)-3-methyl-D-β-aspartyl-L-arginyl-(2S,3S,4E,6E,8S,9S)-3-amino-9-methoxy-2,6,8-trimethyl-10-phenyl-4,6-decadienoyl-D-γ-glutamyl]

Synonyms:  Cyanoginosin-RR

Molecular weight: 1,038.20

CAS: 111755-37-4

Purity: ≥95%

Formulation: A clear film

Product Type|Biochemicals|Natural Products|Microbial Metabolites||Product Type|Biochemicals|Small Molecule Inhibitors|Phosphatases||Product Type|Biochemicals|Toxins|Microcystins||Research Area|Toxicology|Environmental|Aquatic Systems

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