A thiazide diuretic; inhibits norepinephrine- and vasopressin-induced contractions of aortic rings isolated from spontaneously hypertensive rats at a concentration of 100 μM; reduces salt-induced increases in blood pressure in salt-sensitive but not salt-resistant rats without affecting body weight or heart rate

Methyclothiazide – 10 mg

Brand:
Cayman
CAS:
135-07-9
Storage:
-20
UN-No:
Non-Hazardous - /

Methylclothiazide is a thiazide diuretic.{40455} It inhibits norepinephrine- (Item No. 16673) and vasopressin-induced contractions of aortic rings isolated from spontaneously hypertensive rats at a concentration of 100 μM. Methylclothiazide reduces salt-induced increases in blood pressure in salt-sensitive but not salt-resistant rats without affecting body weight or heart rate.{40454} Formulations containing methylclothiazide have been used to treat hypertension.  

 

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SKU: 23799 - 10 mg Category:

Description

A thiazide diuretic; inhibits norepinephrine- and vasopressin-induced contractions of aortic rings isolated from spontaneously hypertensive rats at a concentration of 100 μM; reduces salt-induced increases in blood pressure in salt-sensitive but not salt-resistant rats without affecting body weight or heart rate

Formal name: 6-chloro-3-(chloromethyl)-3,4-dihydro-2-methyl-2H-1,2,4-benzothiadiazine-7-sulfonamide, 1,1-dioxide

Synonyms:  NSC 110431

Molecular weight: 360.2

CAS: 135-07-9

Purity: ≥98%

Formulation: A solid

Product Type|Biochemicals||Research Area|Cardiovascular System|Blood|Serum Proteins||Research Area|Cardiovascular System|Cardiovascular Diseases|Hypertension||Research Area|Cardiovascular System|Kidney & Renal Disease||Research Area|Cardiovascular System|Vasculature|Vasodilation

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