A succinimide that is converted to N-desmethylmethosuximide

Methsuximide – 50 mg

Brand:
Cayman
CAS:
77-41-8
Storage:
-20
UN-No:
Non-Hazardous - /

Methsuximide is a succinimide that is converted to N-desmethylmethosuximide, a channel blocker that targets low threshold calcium currents.{31826,31827} Methsuximide is a substrate of cytochrome P450 (CYP) isoform 2C19 that, in turn, inhibits CYP2C19-mediated metabolism of biguanides.{28279} Methsuximide has been shown to have anticonvulsant properties in clinical trials.{31828,31829}  

 

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Description

A succinimide that is converted to N-desmethylmethosuximide, a channel blocker that targets low threshold calcium currents; inhibits CYP2C19-mediated metabolism of biguanides; has anticonvulsant properties in clinical trials

Formal name: 1,3-dimethyl-3-phenyl-2,5-pyrrolidinedione

Synonyms:  (±)-Mesuximide|PM 396

Molecular weight: 203.2

CAS: 77-41-8

Purity: ≥98%

Formulation: A crystalline solid

Product Type|Biochemicals|Ion Channel Modulation|Blockers||Product Type|Biochemicals|Small Molecule Inhibitors|Cytochrome P450||Research Area|Neuroscience|Seizure Disorders

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