A fungicide; inhibits protein synthesis in fungi; inhibits the growth of potato blight fungal isolates from Serbian potato fields (EC50s = 0.3-3.9 μg/ml); induces formation of chromosomal aberrations in human lymphocytes at 300 and 1

Metalaxyl – 100 mg

Brand:
Cayman
CAS:
57837-19-1
Storage:
-20
UN-No:
Non-Hazardous - /

Metalaxyl is a fungicide that inhibits protein synthesis in fungi.{43133,42434} It inhibits the growth of potato blight (P. infestans) fungal isolates from Serbian potato fields (EC50s = 0.3-3.9 μg/ml).{43133} Metalaxyl (300 and 1,000 μg/ml) induces formation of chromosomal aberrations in human lymphocytes.{42433} It exhibits aquatic toxicity against S. quadricanda, D. magna, and D. rerio (IC50s = 222.89, 471.95, and 241.98 mg/L, respectively).{42435} Metalaxyl also induces tremors, twitches, tonic extension, ataxia, and hypnosis, symptoms of CNS poisoning, and lethality in rats (LD50s = 265 and 288.8 mg/kg for female and male rats, respectively).{42434}  

 

Available on backorder

Add to quotes
SKU: 25817 - 100 mg Category:

Description

A fungicide; inhibits protein synthesis in fungi; inhibits the growth of potato blight fungal isolates from Serbian potato fields (EC50s = 0.3-3.9 μg/ml); induces formation of chromosomal aberrations in human lymphocytes at 300 and 1,000 μg/ml; exhibits aquatic toxicity against S. quadricanda, D. magna, and D. rerio (IC50s = 222.89, 471.95, and 241.98 mg/L, respectively); induces tremors, twitches, tonic extension, ataxia, hypnosis, and lethality in rats (LD50s = 265 and 288.8 mg/kg for female and male rats, respectively)

Formal name: N-(2,6-dimethylphenyl)-N-(2-methoxyacetyl)-alanine, methyl ester

Synonyms:  (±)-Metalaxyl|rac-Metalaxyl

Molecular weight: 279.3

CAS: 57837-19-1

Purity: ≥98%

Formulation: A solid

Product Type|Biochemicals|Pesticides|Fungicides||Research Area|Neuroscience||Research Area|Toxicology|Environmental|Aquatic Systems

Related products

  • CAY10512 is a substituted trans-stilbene analog of resveratrol that is 100-fold more potent as measured by antioxidant activity. The IC50 value for inhibition of TNFα-induced activation of NF-κB by CAY10512 is 0.15 µM compared to 20 µM by resveratrol.{14545}

    CAY10512 – 100 mg

    The nuclear factor-κB (NF-κB) regulates the expression of numerous genes involved in immunity and inflammation, cellular stress responses, growth, and apoptosis. Resveratrol, a polyphenolic trans-stilbene, is a known inhibitor of the activation of NF-κB and exhibits activity against a wide variety of cancer cells. CAY10512 is a substituted trans-stilbene analog of resveratrol that is 100-fold more potent as measured by antioxidant activity. The IC50 value for inhibition of TNFα-induced activation of NF-κB by CAY10512 is 0.15 µM compared to 20 µM by resveratrol.{14545}  

     

    Brand:
    Cayman
    SKU:10009536 - 100 mg

    Available on backorder

    Add to quotes
    Add to quotes
    View product page
  • PtdIns-(3

    PtdIns-(3,4,5)-P3-biotin (sodium salt) – 10 µg

    The PtdIn phosphates play an important role in the generation and transduction of intracellular signals.{8344,4096,14518} PtdIns-(3,4,5)-P3-biotin is an affinity probe which allows the PIP3 to be detected through an interaction with the biotin ligand. This design allows PtdIns-(3,4,5)-P3-biotin to serve as a general probe for any protein with a high affinity binding interaction with inositol-(3,4,5)-triphosphate phospholipids, such as phosphatidylinositol 3-kinase, PTEN, or PH-domain-containing proteins.  

     

    Brand:
    Cayman
    SKU:10009531 - 10 µg

    Available on backorder

    Add to quotes
    Add to quotes
    View product page
  • A potent inhibitor of Cdk2/cyclin E with an IC50 value of 0.1 µM; also inhibits Cdk7/cyclin H

    (R)-Roscovitine – 5 mg

    Cyclin-dependent kinases (CDKs) are key regulators of cell cycle progression and are therefore promising targets for cancer therapy. (R)-Roscovitine is a potent inhibitor of Cdk2/cyclin E with an IC50 value of 0.1 µM.{14988} It also inhibits Cdk7/cyclin H, Cdk5/p35, and cell division cycle (cdc)/cyclin B with IC50 values of 0.49, 0.16, and 0.65 µM, respectively.{14987,14988,14991} (R)-Roscovitine inhibits the growth of rapidly proliferating cells with an average IC50 value of 15.2 µM against a panel of 19 human tumor cell lines.{14988} In murine models of polycystic kidney disease, (R)-roscovitine effectively inhibited disease progression at doses of 50-100 mg/kg.{14564}  

     

    Brand:
    Cayman
    SKU:10009569 - 5 mg

    Available on backorder

    Add to quotes
    Add to quotes
    View product page
  • PtdIns-(3

    PtdIns-(3,4,5)-P3-biotin (sodium salt) – 50 µg

    The PtdIn phosphates play an important role in the generation and transduction of intracellular signals.{8344,4096,14518} PtdIns-(3,4,5)-P3-biotin is an affinity probe which allows the PIP3 to be detected through an interaction with the biotin ligand. This design allows PtdIns-(3,4,5)-P3-biotin to serve as a general probe for any protein with a high affinity binding interaction with inositol-(3,4,5)-triphosphate phospholipids, such as phosphatidylinositol 3-kinase, PTEN, or PH-domain-containing proteins.  

     

    Brand:
    Cayman
    SKU:10009531 - 50 µg

    Available on backorder

    Add to quotes
    Add to quotes
    View product page