A monoterpene with diverse biological activities; inhibits AChE (Ki = 1.25 mM for the bovine enzyme); decreases expression of the genes encoding topoisomerase I

(–)-Menthol – 100 mg

Brand:
Cayman
CAS:
2216-51-5
Storage:
-20
UN-No:
Non-Hazardous - /

(–)-Menthol is a monoterpene that has been found in cornmint oil and has diverse biological activities.{42361} It inhibits acetylcholinesterase (AChE; Ki = 1.25 mM for the bovine enzyme).{54071} (–)-Menthol (1.6 mM) decreases expression of the genes encoding topoisomerase I, IIα, and Iiβ in, and cell viability of, SNU-5 gastric cancer cells.{54072} It is active against the plant pathogenic bacteria A. tumefaciens and E. carotovora (MICs = 2.5 and 4 µg/ml, respectively).{54073} (–)-Menthol (3-10 mg/kg) reduces acetic acid-induced writhing and increases latency to paw licking in a hot plate test in mice.{54074}  

 

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SKU: 30384 - 100 mg Category:

Description

A monoterpene with diverse biological activities; inhibits AChE (Ki = 1.25 mM for the bovine enzyme); decreases expression of the genes encoding topoisomerase I, IIα, and Iiβ in, and cell viability of, SNU-5 gastric cancer cells at 1.6 mM; active against A. tumefaciens and E. carotovora (MICs = 2.5 and 4 µg/ml, respectively); reduces acetic acid-induced writhing and increases latency to paw licking in a hot plate test in mice from 3-10 mg/kg

Formal name: (1R,2S,5R)-5-methyl-2-(1-methylethyl)-cyclohexanol

Synonyms:  ​(1R,2S,5R)-(−)-Menthol|L-Menthol|NSC 62788

Molecular weight: 156.3

CAS: 2216-51-5

Purity: ≥98%

Formulation: A crystalline solid

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