Mensacarcin – 1 mg

Brand:
Cayman
CAS:
808750-39-2
Storage:
-20
UN-No:
Non-Hazardous - /

Mensacarcin is a bacterial metabolite that has been found in S. bottropensis and has anticancer activity.{57141,57140} It is cytostatic in the NCI-60 panel of cancer cell lines (mean IC50 = 1.3 µM) and cytotoxic to HepG2, HM02, KATO III, and MCF-7 cells (IC50s = 0.4-50 µM).{57141} Mensacarcin induces apoptosis in SK-MEL-28 and SK-MEL-5 melanoma cells.{57140}  

 

Available on backorder

SKU: 31438 - 1 mg Category:

Description

A bacterial metabolite with anticancer activity; cytostatic in the NCI-60 panel of cancer cell lines (mean IC50 = 1.3 µM); cytotoxic to HepG2, HM02, KATO III, and MCF-7 cells (IC50s = 0.4-50 µM); induces apoptosis in SK-MEL-28 and SK-MEL-5 melanoma cells


Formal name: (1R,2S,3S,4S,4aS,9aS,10S)-1,2,3,4-tetrahydro-1,3,4-trihydroxy-5,10-dimethoxy-2-methyl-3-[[(2R,3S)-3-methyl-2-oxiranyl]carbonyl]-4a,9a-epoxyanthracen-9(10)-one

Synonyms: 

Molecular weight: 420.4

CAS: 808750-39-2

Purity: ≥98%

Formulation: A solid