Description
MAP kinase kinase 1 (MEK1) is an integral component of the MAP kinase cascade that regulates cell growth and differentiation.{14328,14329} This pathway also plays a key role in synaptic plasticity in the brain.{14327} Activated MEK1 acts as a dual specificity kinase phosphorylating both a threonine and a tyrosine residue on MAP kinase.{14330,14331,14332}
Synonyms: MAP Kinase Kinase ½|MAPKK1/2|Mitogen-activated Protein Kinase Kinase 1/2
Immunogen: phosphopeptide corresponding to amino acid residues surrounding the phospho-Ser218,222 of human MEK1/2
Formulation: Affinity-purified IgG
Isotype:
Applications: WB
Origin: Animal/Rabbit
Stability: 365 days
Application|Western Blot||Product Type|Antibodies|Polyclonal Antibodies||Research Area|Cell Biology|Cell Signaling|ERK/MAPK Signaling