An active metabolite of lidocaine; formed via N-deethylation of lidocaine by hepatic CYP3A4; topical administration reduces thrombus formation in a hamster model of laser-induced microvascular injury at 2% v/v; plasma levels following lidocaine administration have been used to monitor declining liver function in patients with cirrhosis

MEGX (hydrochloride) – 5 mg

Brand:
Cayman
CAS:
7729-94-4
Storage:
-20
UN-No:
De Minimis - 2811 / 6.1

MEGX is an active metabolite of lidocaine.{42862} It is formed via N-deethylation of lidocaine by the hepatic cytochrome P450 (CYP) isoform CYP3A4. Topical administration of MEGX (2% v/v) reduces thrombus formation in a hamster model of laser-induced microvascular injury.{42863} Plasma levels of MEGX following lidocaine administration have been used to monitor declining liver function in patients with cirrhosis.{42862}  

 

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SKU: 28019 - 5 mg Category:

Description

An active metabolite of lidocaine; formed via N-deethylation of lidocaine by hepatic CYP3A4; topical administration reduces thrombus formation in a hamster model of laser-induced microvascular injury at 2% v/v; plasma levels following lidocaine administration have been used to monitor declining liver function in patients with cirrhosis ,

Formal name: N-(2,6-dimethylphenyl)-2-(ethylamino)-acetamide, monohydrochloride

Synonyms:  Monoethylglycinexylidide|Norlidocaine

Molecular weight: 242.7

CAS: 7729-94-4

Purity: ≥95%

Formulation: A solid

Product Type|Biochemicals|Xenobiotic Metabolites||Research Area|Cardiovascular System|Blood|Thrombosis||Research Area|Cardiovascular System|Vasculature||Research Area|Toxicology|Drug Metabolism|Cytochrome P450

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