A synthetic progestogen; prevents fertilization and increases the rate of transport of eggs from the fallopian tubes to the uterus in female ferrets when administered prior to ovulation; reversibly blocks ovulation in rats when injected on the last day of diestrus; has anti-androgenic activity in rats

Medroxyprogesterone 17-acetate – 500 mg

Brand:
Cayman
CAS:
71-58-9
Storage:
4
UN-No:
Non-Hazardous - /

Medroxyprogesterone 17-acetate is a synthetic progestogen.{37205},{37206},{37207} It prevents fertilization and increases the rate of transport of eggs from the fallopian tubes to the uterus in female ferrets when administered prior to ovulation.{37205} Medroxyprogesterone 17-acetate reversibly blocks ovulation in rats when injected on the last day of diestrus.{37206} It also has anti-androgenic activity in rats, decreasing plasma testosterone (Item Nos. 15645 | ISO60154) levels via induction of hepatic testosterone reductase activity.{37207} Medroxyprogesterone 17-acetate exhibits immunosuppressive effects in vitro and in vivo, inhibiting the production of IFN-γ by CD2/CD3/CD28-stimulated peripheral blood mononuclear cells (PBMCs) at concentrations ≥10 nM and extending the survival of rabbit skin allografts.{37208},{37209} Injectable formulations containing medroxyprogesterone 17-acetate have been used as contraceptives.{37210}  

 

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SKU: 23664 - 500 mg Category:

Description

A synthetic progestogen; prevents fertilization and increases the rate of transport of eggs from the fallopian tubes to the uterus in female ferrets when administered prior to ovulation; reversibly blocks ovulation in rats when injected on the last day of diestrus; has anti-androgenic activity in rats, decreasing plasma testosterone levels via induction of hepatic testosterone reductase activity; inhibits production of IFN-γ by CD2/CD3/CD28-stimulated PBMCs and extends the survival of rabbit skin allografts

Formal name: 17-(acetyloxy)-6α-methyl-pregn-4-ene-3,20-dione

Synonyms:  NSC 21171|NSC 26386|U-8839

Molecular weight: 386.5

CAS: 71-58-9

Purity: ≥98%

Formulation: A solid

Product Type|Biochemicals|Lipids|Sterol Lipids||Research Area|Endocrinology & Metabolism|Hormones & Receptors|Estrogens & Progestins||Research Area|Endocrinology & Metabolism|Reproductive Biology||Research Area|Immunology & Inflammation|Adaptive Immunity||Research Area|Immunology & Inflammation|Innate Immunity

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