A progesterone receptor agonist (Ki = 241 nM); a metabolite of medroxyprogesterone 17-acetate; induces a conformational change in the C-terminal domain of the progesterone receptor (EC50 = 47.3 nM); increases alkaline phosphatase activity in T47D breast cancer cells (EC50 = 23 nM)

Medroxyprogesterone – 1 g

Brand:
Cayman
CAS:
520-85-4
Storage:
-20
UN-No:
Non-Hazardous - /

Medroxyprogesterone is a progesterone receptor agonist (Ki = 241 nM) and a metabolite of medroxyprogesterone 17-acetate (Item No. 23664).{42538,42539,42540} It induces a conformational change in the C-terminal domain of the progesterone receptor (EC50 = 47.3 nM) and increases alkaline phosphatase activity in T47D breast cancer cells (EC50 = 23 nM).{42538}  

 

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SKU: 24908 - 1 g Category:

Description

A progesterone receptor agonist (Ki = 241 nM); a metabolite of medroxyprogesterone 17-acetate; induces a conformational change in the C-terminal domain of the progesterone receptor (EC50 = 47.3 nM); increases alkaline phosphatase activity in T47D breast cancer cells (EC50 = 23 nM),,

Formal name: 17-hydroxy-6α-methyl-pregn-4-ene-3,20-dione

Synonyms:  NSC 27408

Molecular weight: 344.5

CAS: 520-85-4

Purity: ≥98%

Formulation: A crystalline solid

Product Type|Biochemicals|Lipids|Sterol Lipids||Product Type|Biochemicals|Receptor Pharmacology|Agonists||Product Type|Biochemicals|Xenobiotic Metabolites||Research Area|Endocrinology & Metabolism|Hormones & Receptors|Estrogens & Progestins

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