An internal standard for the quantification of meclizine by GC- or LC-MS

Meclizine-d8 (hydrochloride) – 500 µg

Brand:
Cayman
CAS:
1432062-16-2
Storage:
-20
UN-No:
Non-Hazardous - /

Meclizine-d8 is intended for use as an internal standard for the quantification of meclizine (Item No. 14615) by GC- or LC-MS. Meclizine is a histamine H1 receptor antagonist (Ki = 250 nM).{23220} Pretreatment with meclizine (2.5-30 mg/kg, i.p.) reduces ovalbumin-induced mast cell degranulation, edema, and leukocyte influx in rat lung.{46070} Formulations containing meclizine have been used in the treatment of motion sickness and vertigo.  

 

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SKU: 26444 - 500 µg Category:

Description

An internal standard for the quantification of meclizine by GC- or LC-MS

Formal name: 1-[(4-chlorophenyl)phenylmethyl]-4-[(3-methylphenyl)methyl]-piperazine-2,2,3,3,5,5,6,6-d8, dihydrochloride

Synonyms: 

Molecular weight: 471.9

CAS: 1432062-16-2

Purity: ≥99% deuterated forms (d1-d8)

Formulation: A solid

Application|Mass Spectrometry||Product Type|Biochemicals|Analytical Standards||Product Type|Biochemicals|Isotopically Labeled Standards|Deuterium||Product Type|Biochemicals|Receptor Pharmacology|Antagonists||Research Area|Immunology & Inflammation|Allergy

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