A fluorogenic substrate for MMP-14; upon cleavage by MMP-14

Mca-PLAC(p-OMeBz)-WAR(Dpa)-NH2 – 500 µg

Brand:
Cayman
CAS:
1926163-82-7
Storage:
-20
UN-No:
Non-Hazardous - /

Mca-PLAC(p-OMeBz)-WAR(Dpa)-NH2 is a fluorogenic substrate for matrix metalloproteinase-14 (MMP-14).{38800} Upon cleavage by MMP-14, 7-methoxycoumarin-4-acetyl (Mca) is released and its fluorescence can be used to quantify MMP activity. Mca displays excitation/emission maxima of 328/420 nm, respectively.  

 

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SKU: 24703 - 500 µg Category:

Description

A fluorogenic substrate for MMP-14; upon cleavage by MMP-14, Mca is released and its fluorescence can be used to quantify MMP activity,

Formal name: 1-[2-(7-methoxy-2-oxo-2H-1-benzopyran-4-yl)acetyl]-L-prolyl-L-leucyl-L-alanyl-S-[(4-methoxyphenyl)methyl]-L-cysteinyl-L-tryptophyl-L-alanyl-L-arginyl-3-[(2,4-dinitrophenyl)amino]-L-alaninamide

Synonyms:  Matrix Metalloproteinase-14 Fluorogenic Substrate I|Mca-Pro-Leu-Ala-Cys(p-OMeBz)-Trp-Ala-Arg(Dpa)-NH2|MMP-14 Fluorogenic Substrate I

Molecular weight: 1,403.50

CAS: 1926163-82-7

Purity: ≥95%

Formulation: A lyophilized powder

Application|Enzyme Activity||Application|Fluorescence||Product Type|Biochemicals|Labeling & Detection|Enzyme Substrates||Product Type|Biochemicals|Labeling & Detection|Fluorescent Probes||Research Area|Cell Biology|Proteolysis

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