A fluorogenic substrate for caspase-3; Mca is released upon cleavage by caspase-3 and its fluorescence can be used to quantify caspase-3 activity

Mca-DEVDAP-K(Dnp)-OH – 1 mg

Brand:
Cayman
CAS:
189696-20-6
Storage:
-20
UN-No:
Non-Hazardous - /

Mca-DEVDAP-K(Dnp)-OH is a substrate for caspase-3.{2549} Upon cleavage by caspase-3, 7-methoxycoumarin-4-acetyl (Mca) is released and its fluorescence can be used to quantify caspase-3 activity. Mca displays excitation/emission maxima of 328/420 nm, respectively.  

 

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SKU: 24563 - 1 mg Category:

Description

A fluorogenic substrate for caspase-3; Mca is released upon cleavage by caspase-3 and its fluorescence can be used to quantify caspase-3 activity, ,

Formal name: N-[(7-methoxy-2-oxo-2H-1-benzopyran-4-yl)acetyl]-L-α-aspartyl-L-α-glutamyl-L-valyl-L-α-aspartyl-L-alanyl-L-prolyl-N6-(2,4-dinitrophenyl)-L-lysine

Synonyms:  7-Methoxycoumarin-4-acetyl-DEVDAPK(Dnp)-OH|Caspase-3 Fluorogenic Substrate III|CPP32 Fluorogenic Substrate III|Mca-Asp-Glu-Val-Asp-Ala-Pro-Lys(Dnp)-OH

Molecular weight: 1,155.10

CAS: 189696-20-6

Purity: ≥95%

Formulation: A lyophilized powder

Application|Enzyme Activity||Application|Fluorescence||Product Type|Biochemicals|Labeling & Detection|Enzyme Substrates||Product Type|Biochemicals|Labeling & Detection|Fluorescent Probes||Research Area|Cell Biology|Cell Death|Apoptosis||Research Area|Cell Biology|Proteolysis|Cytosolic & Secreted Proteases

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