An antibiotic that is cytotoxic against Cryptosporidium spp. and Plasmodium gametocytes

Maduramicin – 25 mg

Brand:
Cayman
CAS:
79356-08-4
Storage:
-20
UN-No:
Non-Hazardous - /

Maduramicin is a natural polyether ionophore antibiotic first isolated from the actinomycete Actinomadura rubra.{32118,32120} It is cytotoxic against Cryptosporidium spp. and is commonly used in veterinary medicine as an anti-coccidial agent.{32118,32120} Maduramicin is also cytotoxic against Plasmodium gametocytes and potentiates the gametocytocidal activity of the pyrazoleamide PA21A050.{32119}  

 

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SKU: 20583 - Category:

Description

An antibiotic that is cytotoxic against Cryptosporidium spp. and Plasmodium gametocytes

Formal name: (2R,3S,4S,5R,6S)-6-[(1R)-1-[(2S,5R,7S,8R,9S)-2-[(2S,2’R,3’S,5R,5’R)-3′-[(2,6-dideoxy-3,4-di-O-methyl-β-L-arabino-hexopyranosyl)oxy]octahydro-2-methyl-5′-[(2S,3S,5R,6S)-tetrahydro-6-hydroxy-3,5,6-trimethyl-2H-pyran-2-yl][2,2′-bifuran]-5-yl]-9-hydroxy-2,8-dimethyl-1,6-dioxaspiro[4.5]dec-7-yl]ethyl]tetrahydro-2-hydroxy-4,5-dimethoxy-3-methyl-2H-pyran-2-acetic acid

Synonyms:  Antibiotic X 14868A

Molecular weight: 917.1

CAS: 79356-08-4

Purity: ≥98%

Formulation: A solid

Product Type|Biochemicals|Antiparasitics|Antiprotozoals||Product Type|Biochemicals|Natural Products|Microbial Metabolites||Research Area|Immunology & Inflammation||Research Area|Infectious Disease|Parasitic Diseases

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